Thick Filament Length and Isoform Composition Determine Self-Organized Contractile Units in Actomyosin Bundles
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چکیده
منابع مشابه
Thick filament length and isoform composition determine self-organized contractile units in actomyosin bundles.
Diverse myosin II isoforms regulate contractility of actomyosin bundles in disparate physiological processes by variations in both motor mechanochemistry and the extent to which motors are clustered into thick filaments. Although the role of mechanochemistry is well appreciated, the extent to which thick filament length regulates actomyosin contractility is unknown. Here, we study the contracti...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2013
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2012.12.042